{"id":2050,"date":"2023-06-07T08:03:44","date_gmt":"2023-06-07T08:03:44","guid":{"rendered":"https:\/\/ptbf.pl\/?p=2050"},"modified":"2023-06-07T08:03:44","modified_gmt":"2023-06-07T08:03:44","slug":"job-offer-phd-student-position-in-transient-receptor-potential-channels-and-t-cell-physiology","status":"publish","type":"post","link":"https:\/\/ptbf.pl\/?p=2050","title":{"rendered":"Job Offer: PhD Student Position in Transient Receptor Potential Channels and T Cell Physiology"},"content":{"rendered":"<p><strong>Department of Physics and Biophysics\/Institute of Biology<br \/>\nWarsaw University of Life Sciences, Warsaw, Poland<\/strong><\/p>\n<p>We are seeking a highly motivated and talented PhD student to join our research team at the Department of Physics and Biophysics, Institute of Biology at Warsaw University of Life Sciences. This position is a valuable opportunity for a passionate individual to contribute to cutting-edge research in the field of T cell biology and immune response, with a specific focus on the role of Transient Receptor Potential Ankyrin 1 (TRPA1) and Melastatin 2 (TRPM2) channels in relation to hypoxia and the regulation of immune response.<\/p>\n<p><strong>Project Overview:<\/strong><\/p>\n<p>The primary objective of this project is to investigate the role of TRPA1 and TRPM2 channels in the physiology of T cells, particularly in relation to hypoxia and their potential involvement in the regulation of immune response. T lymphocytes, as crucial components of the adaptive immune system, play a pivotal role in combating pathogens, including viruses, and are involved in cancer and autoimmune disorders. However, the intricate regulation of T cell functioning is influenced by multiple factors, such as temperature, pH, and hypoxia. Hypoxia, in particular, is known to have a detrimental impact on T cell physiology, affecting their activation, cytotoxicity, and metabolism. The project aims to explore the link between hypoxia-sensing, TRPA1 and TRPM2 channels, and their potential influence on T cells physiology.<!--more--><\/p>\n<p><strong>Responsibilities:<\/strong><\/p>\n<ul>\n<li>Isolation of primary T cells from human blood samples and T cells culture,<\/li>\n<li>Performing molecular biology techniques, including RNA extraction, cDNA synthesis, and quantitative PCR (qPCR) analysis,<\/li>\n<li>Conducting Western Blot analysis to determine protein expression levels,<\/li>\n<li>Performing enzyme-linked immunosorbent assay (ELISA) for cytokine analysis,<\/li>\n<li>Employing flow cytometry to analyze T cells phenotype and function,<\/li>\n<li>Designing and executing experimental protocols, including data collection, analysis, and interpretation<\/li>\n<li>Collaborating with fellow researchers, presenting findings at scientific conferences, and contributing to scientific publications<\/li>\n<li>Conducting comprehensive literature reviews to establish a strong foundation in the research area<\/li>\n<\/ul>\n<p><strong>Requirements:<\/strong><\/p>\n<ul>\n<li>A Master&#8217;s degree (M.Sc) in biology, biotechnology, or a related discipline<\/li>\n<li>Strong background in cell culture and molecular biology techniques, experience in T cell isolation, cell culture, qPCR, Western Blot, ELISA or flow cytometry techniques will be advantageous<\/li>\n<li>Excellent analytical and problem-solving skills<\/li>\n<li>Ability to work independently and as part of a team<\/li>\n<li>Fluency in written and spoken English<\/li>\n<\/ul>\n<p><strong>Benefits:<\/strong><\/p>\n<ul>\n<li>Gross salary 5000 PLN per month,<\/li>\n<li>Collaboration opportunities with experts and researchers in the field,<\/li>\n<li>Possibility for professional development, including workshops and conferences,<\/li>\n<li>Supportive supervisors and mentors to guide you throughout your PhD journey,<\/li>\n<\/ul>\n<p><strong>Application Procedure:<\/strong><\/p>\n<p>To apply for this position, please submit the following documents as a single PDF file via email to <a href=\"mailto:joanna_bujak@sggw.edu.pl\">joanna_bujak@sggw.edu.pl<\/a>:<\/p>\n<ul>\n<li>a detailed curriculum vitae (CV) highlighting your academic qualifications and research experience<\/li>\n<li>a cover letter describing your research interests, motivation, and why you believe you are a suitable candidate for this position<\/li>\n<li>copies of academic transcripts and degree certificates<\/li>\n<li>contact information of two professional references who can provide letters of recommendation<\/li>\n<li>selected candidate is required to apply for admission to the doctoral school (please find more information about recruitment to the doctoral school here: <a href=\"https:\/\/www.sggw.edu.pl\/en\/home\/science\/doctoral-school\/recruitment-to-doctoral-school\/\">https:\/\/www.sggw.edu.pl\/en\/home\/science\/doctoral-school\/recruitment-to-doctoral-school\/<\/a> )<\/li>\n<\/ul>\n<p>Application Deadline: August 15, 2023<\/p>\n","protected":false},"excerpt":{"rendered":"<a href=\"https:\/\/ptbf.pl\/?p=2050\"><img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"http:\/\/ptbf.pl\/wp-content\/plugins\/thumbnail-for-excerpts\/tfe_no_thumb.png\" class=\"alignleft wp-post-image tfe\" alt=\"\" title=\"\" \/><\/a><p>Department of Physics and Biophysics\/Institute of Biology Warsaw University of Life Sciences, Warsaw, Poland We are seeking a highly motivated and talented PhD student to join our research team at the Department of Physics and Biophysics, Institute of Biology at &hellip; <a href=\"https:\/\/ptbf.pl\/?p=2050\">Czytaj dalej <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[3],"tags":[],"class_list":["post-2050","post","type-post","status-publish","format-standard","hentry","category-aktualnosci"],"_links":{"self":[{"href":"https:\/\/ptbf.pl\/index.php?rest_route=\/wp\/v2\/posts\/2050","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ptbf.pl\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ptbf.pl\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ptbf.pl\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/ptbf.pl\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2050"}],"version-history":[{"count":1,"href":"https:\/\/ptbf.pl\/index.php?rest_route=\/wp\/v2\/posts\/2050\/revisions"}],"predecessor-version":[{"id":2051,"href":"https:\/\/ptbf.pl\/index.php?rest_route=\/wp\/v2\/posts\/2050\/revisions\/2051"}],"wp:attachment":[{"href":"https:\/\/ptbf.pl\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2050"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ptbf.pl\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2050"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ptbf.pl\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2050"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}